Regulatory
Part:BBa_K511001:Design
Designed by: Grant Robinson Group: iGEM11_MIT (2011-09-25)
minCMV-1xCI434 Promoter MammoBlock
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This particular promoter has a propensity to mutate in cells that are not exceptionally recombination-deficient, and caution should be taken in producing both entry and expression vectors using this part.
Source
This promoter is a synthetic construct composed of the minimal sequence required for transcription from the immediate-early cytomegalovirus (CMV) promoter preceded by a binding site for the CI434 protein adapted from bacteriophage 434. Sincere thanks go to Noah Davidsohn for contributing this entry vector to the MIT iGEM 2011 team.